Particle Separation: Anticipating Cutoff Diameters in Deterministic Lateral Displacement (DLD) Microfluidic Devices for an Optimized Particle Separation (Small 37/2017)
نویسندگان
چکیده
منابع مشابه
Particle Separation with Deterministic Lateral Displacement ( DLD ) : The Anisotropy Effect †
Deterministic lateral displacement (DLD) is a passive and label-free microfluidic separation technique with a strong potential for biological sample preparation purposes. Numerical and experimental models have been proposed so far to predict the particle behavior in DLD channels. However, they do not take into account the influence of the pillar anisotropy that induces a secondary pressure grad...
متن کاملContinuous particle separation through deterministic lateral displacement.
We report on a microfluidic particle-separation device that makes use of the asymmetric bifurcation of laminar flow around obstacles. A particle chooses its path deterministically on the basis of its size. All particles of a given size follow equivalent migration paths, leading to high resolution. The microspheres of 0.8, 0.9, and 1.0 micrometers that were used to characterize the device were s...
متن کاملElectrokinetically driven deterministic lateral displacement for particle separation in microfluidic devices
migrating in different directions with respect to the array, thus causing the two-dimensional and continuous fractionation of the mixture (Huang et al. 2004; Inglis et al. 2006). Microfluidic DLD devices have been successfully applied to the fractionation of different mixtures, and in particular for cell sorting and the separation of biological material (Xuan and Lee 2013; Davis et al. 2006; Li...
متن کاملDeterministic lateral displacement for particle separation: a review.
Deterministic lateral displacement (DLD), a hydrodynamic, microfluidic technology, was first reported by Huang et al. in 2004 to separate particles on the basis of size in continuous flow with a resolution of down to 10 nm. For 10 years, DLD has been extensively studied, employed and modified by researchers in terms of theory, design, microfabrication and application to develop newer, faster an...
متن کاملDirectional locking in deterministic lateral-displacement microfluidic separation systems.
We analyze the trajectory of suspended spherical particles moving through a square array of obstacles, in the deterministic limit and at zero Reynolds number. We show that in the dilute approximation of widely separated obstacles, the average motion of the particles is equivalent to the trajectory followed by a point particle moving through an array of obstacles with an effective radius. The ef...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Small
سال: 2017
ISSN: 1613-6810
DOI: 10.1002/smll.201770201